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        Sub-threshold

        It is possible that procedures authorised under a project licence could result in below threshold severity. This occurs when a procedure was originally considered to cause above-threshold pain or suffering, but in retrospect this did not occur. This can include:

        • breeding of genetically altered animals under project licence authority but without a harmful phenotype
        • dosing with a compound in feed where the animals ate normally and suffered no consequences of being dosed

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